Chronic carotid compression in dogs: a study of hemodynamic changes with and without sinus denervation.

• Wakerlin and his associates have reported' 2 that chronic bilateral carotid sinus compression in dogs resulted in a sustained elevation of the mean arterial pressure. This finding was confirmed by Hawthorne and Gaspar, who reported also that the elevated mean arterial pressure after bilateral carotid sinus compression was ameliorated by hypophysectomy. Kezdi reported that bilateral constriction of the external and internal carotid arteries did not result in an elevation of mean arterial pressure in the dog; subsequent section of the carotid sinus nerves bilaterally did result in a sustained elevation of mean arterial pressure.